Expert Pharma Discovery Biologist

Cogent Scientific

Posted 3 months ago

Full Time

South San Francisco, California

In Person

Smart Summary

Responsibilities

Lead in vitro discovery biology for oncology programs, focusing on target validation and candidate selection across various therapeutic modalities. Design and execute cell-based assays and mechanistic studies to characterize target engagement and mechanism of action.

Qualifications

You have a PhD in Molecular Biology, Biochemistry, or a related field, with 0-2 years of industry or postdoctoral experience in oncology drug discovery or targeted therapeutics research. You possess excellent communication and problem-solving skills, demonstrating strong attention to detail and the ability to work effectively both independently and within a team in a fast-paced environment.

Must Have Skills for ATS

oncology drug discovery

targeted therapeutics

in vitro discovery biology

target validation

target identification

pathway biology

cell-based assays

Western blot

phosphoproteomics

target engagement

mechanism of action

receptor internalization

3D culture systems

co-culture platforms

Job Description

Cogent Scientific, an insourced contract research organization, is looking for the right people to accomplish our Mission: to support the life sciences industry with specialized laboratory services delivered by professional scientists—advancing research, fostering collaboration, and accelerating innovation with quality and a commitment to excellence.  We can offer you the chance to build on your skills and knowledge while working among experts in their fields and with cutting-edge instrumentation.

Cogent Scientific offers competitive pay, attractive benefits (such as medical/dental/vision insurance; 401(k); parental leave; PTO and paid holidays; etc.) and an exciting work environment.  This position may include relocation benefits as well.  We aim to recruit the best people who stand out among their peers and embody our Core Values:

• Client Focused: We only succeed when our clients succeed.
• Outstanding: We deliver meticulous results through outstanding performance.
• Good: We act ethically and morally.
• Employee-Centric: We honor and support our employees.
• Nimble: We are prepared to adapt in an ever-changing industry.
• Team-Oriented: We collaborate with each other and with our clients.

We currently have a role available for an Expert Pharma Discovery Biologist.

Job duties include, but are not limited to:

  • Leading in vitro discovery biology across oncology programs, from early target validation through candidate selection, spanning multiple therapeutic modalities.
  • Contributing to target identification and prioritization by integrating literature, pathway biology, and emerging clinical and preclinical data to nominate and validate novel therapeutic targets.
  • Designing and executing cell-based assays to evaluate compound activity, including viability, proliferation, and apoptosis readouts across relevant tumor models.
  • Driving mechanistic and signaling studies (e.g., Western blot, phosphoproteomics, pathway analysis) to characterize target engagement and mechanism of action.
  • Leading target biology efforts including evaluation of target expression, antigen density, receptor internalization, intracellular trafficking, and target-dependent processing.
  • Developing and optimizing disease-relevant in vitro models (e.g., 3D culture systems, model generation, co-culture platforms) to characterize novel modalities and enable translational studies.

Job requirements include, but are not limited to:

  • PhD in Molecular Biology, Biochemistry or related field with 0-2 years of industry or relevant postdoctoral experience in oncology drug discovery or targeted therapeutics research.
  • Excellent communication skills – verbal and written.
  • Works well both within a team and as an individual.
  • Demonstration of excellent team player and collaboration skills, very strong attention to detail, very strong problem-solving skills, a high level of learning agility, and the ability to work across functions.
  • The ideal candidate will be enthusiastic and self-motivated, with the leadership and communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery.

This is a day shift position (approx. 8a-5p local time).

Cogent Scientific provides equal employment opportunities to all applicants and does not discriminate based on any legally protected characteristic.

Additionally, if you require a reasonable accommodation during the application or interview process, please let us know.

This job posting will close by 7/6/2026 or when a candidate is identified, whichever comes first.

Cogent Scientific

The pharmaceutical and biotech industries experienced a tremendous amount of change this past decade. For companies to remain relevant and competitive, they must respond quickly and effectively to the unique challenges they face. Our company was started to assist companies in navigating these hurdles. Cogent has earned a reputation for reliability regarding our partnership to our clients. We believe that the key to maintaining that commitment is attracting and retaining good people to be part of our team. Our commitment to our clients is intertwined with our commitment to our employees. Cogent employs talented individuals who also bring a positive, team oriented approach to the tasks at hand. Each day, our people demonstrate their motivation and initiative to make things simple and to innovate while being empowered by the drive to make the right decisions. This passion for excellence means our customers trust our partnership and employees choose to join – and stay with – Cogent Scientific.
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