Demeetra is seeking a highly motivated Cell Line Development Scientist to join our fast-paced team advancing next-generation gene editing technologies in bioproduction. This role is designed for someone who is eager, hands-on, detail-driven, and experienced enough to contribute with minimal onboard training. The successful candidate must be driven by a culture of excellence and ready for intense, high-expectation, hands-on CLD workflows, bringing industry experience that enables them to contribute at a high level from day one, ideally in a CRO or CDMO setting.

About the Role

You will be a key contributor in developing engineered CHO cell lines and optimizing upstream processes that support Demeetra’s cutting-edge gene editing platforms. This position is ideal for recent graduates (MS or PhD) and are eager to take ownership of experimental design, workflow execution, and timeline-driven deliverables.

Responsibilities

Execute CHO cell culture processes across shake flasks and spin tube fed-batch formats
Perform transfection, selection, single-cell cloning, and clone characterization workflows
Support upstream development with high attention to process consistency and data integrity
Vector design and molecular biology
Run titer and basic downstream quality assays to assess productivity and cell line performance, analytical experience (HPLC) is a plus.
Collaborate cross-functionally to implement advanced gene editing technologies in CLD
Contribute to workflow design, documentation, and continuous process improvement
Maintain a culture of excellence, accountability, and meeting or exceeding timelines

Required Qualifications

MS or PhD in biology, biochemistry, biotechnology, or related field required
Demonstrated proficiency in:
- Molecular biology and vector construction
- Suspension CHO cell culture
- Transfection & selection workflows
- Shake flask, spin tube, and deep-well plate fed-batch processes
- Single-cell cloning
- Titer determination and standard downstream quality assessments
- Analytical techniques such as HPLC, LC/MS, and/or CE.
Ability to thrive in a high-expectation, fast-moving environment
Strong communication, organization, and documentation skills

Why Join Demeetra?

This is an opportunity to join a growing company at the forefront of gene editing applied to cell line development and bioprocessing. You will have significant hands-on impact, work with advanced technologies, and be part of an intensely collaborative and rewarding environment.

Industry

Biotechnology Research

Employment Type

Full-time

Demeetra empowers biomanufacturers and researchers to move rapidly from precise gene edits to high-yield expression using a suite of proprietary, commercially accessible technologies. Our solutions optimize cell line development while eliminating common licensing and scalability barriers. Our Technologies: • Cas-CLOVER™: A high-fidelity nuclease that delivers clean, efficient gene knockouts and targeted knock-ins, with performance that rivals or exceeds CRISPR/Cas9. • Harbor-IN™: A license-free transposase that enables stable integration of large genetic payloads, achieving high titers without royalties or downstream fees. • CleanCut™ Host Cell Portfolio: Features a suspension CHO GS knockout line and an expanding collection of pre-engineered cell lines optimized for productivity and feature flexibility, accelerating your path to milestone success. Why Demeetra: • Editing Efficiency Meets Business Clarity: From superior editing precision to simplified licensing models, we remove the barriers that slow scientific and commercial progress. • Clear Freedom to Operate: Straightforward licensing backed by issued patents and strategic foundational CRISPR/Cas9 agreements. • No Royalties or Milestone Fees: Keep your autonomy with zero downstream restrictions or sublicensing complications. • Enhanced Performance: Achieve larger knock-ins, higher expression yields, and cleaner edits than traditional Cas9 or other transposase systems. Whether you’re advancing research or scaling a biotherapeutic pipeline, Demeetra equips your team with the tools and freedom to move forward faster and with confidence.

Cell Line Development Scientist

Cell Line Development Scientist

Boost Your Interview Chances