Scientific Intern, Analytical Development

A

Arcturus Therapeutics Inc

Posted 3 months ago

Internship

San Diego, California

In Person

Smart Summary

Responsibilities

The intern will perform routine analytical testing of RNA-based drug substances, intermediates, and formulated products using various specialized instruments. Additionally, they will support equipment maintenance, manage inventory, and document experimental results.

Qualifications

You are currently pursuing a bachelor's degree in Analytical Chemistry or a related field. You have hands-on experience with wet bench laboratory techniques and proficiency in operating standard laboratory instruments and computer software.

Must Have Skills for ATS

Chromatography

Spectroscopy

Electrophoresis

Particle characterization

UV-Vis

Karl Fischer

Fluorescent plate readers

Osmometers

Viscometers

Biochemistry techniques

Job Description

WHY WORK FOR ARCTURUS?

Founded in 2013 and based in San Diego, California, Arcturus Therapeutics Holdings Inc. (Nasdaq: ARCT) is a clinical-stage mRNA medicines and vaccines company with enabling technologies: (i) LUNAR® lipid-mediated delivery, (ii) STARR™ mRNA Technology and (iii) mRNA drug substance along with drug product manufacturing expertise. Arcturus’ diverse pipeline of RNA therapeutic and vaccine candidates includes self-replicating mRNA vaccine programs for SARS-CoV-2 (COVID-19) and Influenza, and other programs to potentially treat Ornithine Transcarbamylase (OTC) Deficiency, Cystic Fibrosis, Cardiovascular Disease along with partnered programs including Glycogen Storage Disease Type 3, Hepatitis B Virus, and non-alcoholic steatohepatitis (NASH). Arcturus’ versatile RNA therapeutics platforms can be applied toward multiple types of nucleic acid medicines including messenger RNA, small interfering RNA, replicon RNA, antisense RNA, microRNA, DNA, and gene editing therapeutics. 

Arcturus’ technologies are covered by its extensive patent portfolio (192 patents and patent applications, issued in the U.S., Europe, Japan, China and other countries). Arcturus’ commitment to the development of novel RNA therapeutics has led to collaborations with Janssen Pharmaceuticals, Inc., part of the Janssen Pharmaceutical Companies of Johnson & Johnson, Ultragenyx Pharmaceutical, Inc., Takeda Pharmaceutical Company Limited, CureVac AG, Synthetic Genomics Inc., Duke-NUS, and the Cystic Fibrosis Foundation. 

Arcturus Therapeutics is presently recruiting outstanding candidates with experience in the field of mRNA technologies and nanoparticle sciences. 

Our corporate culture is dynamic, diverse, and creative. We value collaboration and teamwork. We seek individuals to join us with a genuine passion for the science behind helping to cure disease and improve the lives of patients.

Job Overview:

The Analytical Intern will support a dynamic and diverse research pipeline by performing routine analytical testing of RNA-based drug substances, intermediates, and formulated drug products. This part-time role is designed for students currently pursuing a bachelor’s degree in Analytical Chemistry or a related discipline.

Responsibilities:

  • Perform and coordinate routine analytical testing of RNA-based drug substances, intermediates, and formulated drug products using a variety of analytical techniques and specialized instrumentation, including chromatography, spectroscopy, electrophoresis, particle characterization, and other relevant methods.
  • Support analytical equipment maintenance, trouble shooting and qualifications.
  • Support organizing, storage and maintaining inventory of analytical materials and supplies.
  • Maintain proper documentation of all experimental procedures and results.
  • Present scientific results and observations to colleagues and management.
  • Perform other duties as needed.

  Primary Outcomes: 

  • Perform and organize routine analytical testing of RNA-based samples in timely manner, be integral member of the team, clearly communicate results and outcomes.

Requirements:

  • Education Required: Student currently pursuing a bachelor's degree in Analytical Chemistry or a related field.
  • Experience Required: Hands-on experience with wet bench laboratory techniques.
  • Strong motivation to learn and grow within a scientific environment.
  • Proficiency in operating standard laboratory instruments as well as computer hardware and software.

Competencies:

  • Experience with analytical characterization of nucleic acid-based therapeutics is a plus.
  • Knowledge of biochemistry techniques
  • Pipetting skills
  • Expertise in multiple analytical techniques such as UV-Vis, Karl Fischer, fluorescent plate readers, osmometers, viscometers etc. is a plus.
  • Demonstrated experience in analysis of molecular biology and biochemistry data.
  • Ability to apply existing knowledge and experience to solve standard analytical problems without instruction and receive guidance on new assignments or more complex problems from a senior team member.
  • Ability to handle large amounts of data without compromising quality of the results

Planning & Organizational:

  • Ability to think critically and creatively, have great attention to details.
  • Have strong organizational and planning skills.
  • Skilled in balancing independent work with teamwork, contributing effectively within an integrated, multi-group environment.
  • Comfortable working in a highly innovative environment and strong ability to cope with change.

Interpersonal:

  • Excellent communication skills when communicating with management, colleagues, peers and other departments.
  • Must be friendly, possess good interpersonal skills.
  • Treats people with respect; Keeps commitments; Works with integrity and ethically.
  • Must be a team player.

 Communication:

  • Strong verbal and written communication abilities
  • Ability to write clearly, concisely, and with attention to detail
  • Skilled in presenting and explaining numerical data effectively
  • Capable of reading, understanding, and interpreting technical and written information

WHAT WE OFFER

An exciting opportunity to join a company that offers a competitive total rewards package that includes:

  • Catered lunches
  • Free variety of snacks and beverages
  • On Campus Gym 
  • Company sponsored FUN events

For a deeper dive into our company and corporate culture visit www.ArcturusRx.com

A

Arcturus Therapeutics Inc

Founded in 2013 and based in San Diego, California, Arcturus Therapeutics Holdings Inc. (Nasdaq: ARCT) a commercial messenger RNA medicines company focused on the development of liver and respiratory rare disease therapeutics and infectious disease vaccines with enabling technologies: (i) LUNAR® lipid-mediated delivery, (ii) STARR® mRNA technology (sa-mRNA) and (iii) mRNA drug substance along with drug product manufacturing expertise. Arcturus developed KOSTAIVE®, the first self-amplifying messenger RNA (sa-mRNA) COVID vaccine in the world to be approved. Arcturus has an ongoing global collaboration for innovative mRNA vaccines with CSL Seqirus, and a joint venture in Japan, ARCALIS, focused on the manufacture of mRNA vaccines and therapeutics. Arcturus’ pipeline includes RNA therapeutic candidates to potentially treat OTC deficiency and cystic fibrosis (CF), along with its partnered mRNA vaccine programs for SARS-CoV-2 (COVID-19) and influenza. Arcturus’ versatile RNA therapeutics platforms can be applied toward multiple types of nucleic acid medicines including messenger RNA, small interfering RNA, circular RNA, antisense RNA, self-amplifying RNA, DNA, and gene editing therapeutics. Arcturus' technologies are covered by its extensive patent portfolio (over 500 patents and patent applications in the U.S., Europe, Japan, China, and other countries).
Runway Icon
Boost Your Interview Chances

With Runway

See Your Fit for This Role

1-5 min

Your Score

?

Top Applicants

90%

Your Job Search Advantage

Key Gaps & Next Steps:

Address these in your resume & Interview

Top Strengths For This Role

Highlight these in your cover letter & interview

Your Interview Guide

A Personalized Interview Strategy

Freshest Opportunities

Never Miss a Good Fit

Get notified when jobs mach your criteria