The Thomas Lab in the Department of Microbiology and Molecular Genetics at the University of Pittsburgh School of Medicine is seeking a highly motivated Postdoctoral Associate to join our team.

Our research investigates how recurrent mutations in PACS1 and PACS2 drive severe neurodevelopmental disorders. We focus on the impact of these mutations on microtubule-based transport, membrane contact sites, and calcium homeostasis in vivo. A central goal of the lab is to understand how de novo variants in these genes disrupt proteostasis, neuronal metabolism, and neurotransmission.

The successful Candidate will employ a combination of cell and molecular biology approaches alongside systems-level techniques, including metabolomics, proteomics, and RNA sequencing, to dissect disease mechanisms. This position offers the opportunity to contribute to ongoing NIH-funded projects in a collaborative and interdisciplinary research environment.

Qualifications

• PhD in cell biology, neurobiology, or a related discipline
• Strong background in laboratory-based research
• Demonstrated experience with cell and molecular biology techniques
• Familiarity with omics approaches (metabolomics, proteomics, RNA-seq) is highly desirable

• Ability to work independently and as part of a team, with strong problem-solving skills  

  Qualified candidates, please apply to requisition # 26002360 at this link: Home | Talent Center: Careers at Pitt | University of Pittsburgh