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The Opportunity:

A Postdoctoral Fellow position is available for a highly motivated and independent candidate to join the laboratory of Dr. Peter Hsu in the Department of Structural Biology at Genentech to answer fundamental questions in both chromatin biology and ubiquitination pathways using biochemical and structural biology tools.

The Hsu Lab works on the biochemical and structural mechanisms of large, multi-subunit protein complexes, with an emphasis on chromatin regulatory factors and E3 ubiquitin ligases involved in key cellular processes. In this role, you will have access to state-of-the-art structural biology and biophysical equipment and facilities, including a well-equipped cryoEM core for both single particle and tomography applications. In addition, you will have opportunities to collaborate with other labs both within Genentech and in academia, and present your work at conferences.

Who You Are:

• Ph.D. with a proven track record of creativity, rigor, and success in structural biology, biochemistry, or a related field, as exemplified by first author publication(s) in high impact journals.

• Successful experience with expression and purification of multi-protein complexes from multiple sources is required.

• Experience with X-ray crystallography and/or single-particle cryoEM is required.

• Independent and capable of designing, executing, and troubleshooting complex experiments to answer challenging scientific questions.

• A strong collaborative spirit to work with others in a team to bring projects to fruition is needed.

• Strong oral and written communication skills are required.

Preferred Qualifications:

• Successful examples of structural determination by single particle cryoEM and/or X-ray crystallography.

• Experience with chromatin and/or ubiquitin biochemistry.

• Experience with protein engineering, biophysical methods for protein-protein and protein-nucleic acid interactions, or assay development.

For information about the Hsu lab, please go to:

https://scholar.google.com/citations?user=FiSzWjAAAAAJ&hl=en&authuser=1

The expected salary range for this position based on the primary location of South San Francisco California is $100,000 to $106,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  This position also qualifies for the benefits detailed at the link provided below.

Benefits

Relocation benefits are available for this job posting.

Postdoc Program

Elevate your research career to new heights with Genetech’s Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions.

The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader.

The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential!

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